GENOTROPIN

 Description:

• Genotropin is synthetically produced somatropin. 
• Somatropin is a pituitary hormone that is necessary for normal growth in children. 
• The hormone is also important for, among other things, the breakdown of fats, carbohydrates and proteins, and is used to maintain normal body composition in both children and adults.

Genotropin is used for growth disorders in children due to:

• Inhibited growth as a result of insufficient secretion of growth hormone.
• Growth disorders associated with Turner syndrome. Occurs only in women. 
• Due to chromosomal defects (XO) with, among other things, short stature and insufficient pubertal development.
• Growth disorders as a result of chronic renal failure.
• Prader-Willi syndrome for improving growth and body composition. Can occur in both sexes. Due to chromosomal defects with, among other things, small external genitalia, delayed or incomplete puberty, increased appetite leading to obesity, short stature and mental retardation.
• Growth disorders in children with short height who were born small for gestational age (SGA).
• For adults, Genotropin is used in the treatment of pronounced growth hormone deficiency. 
• This can occur in adulthood, or it can be a condition one has had since childhood.
• If you have been treated with Genotropin for growth hormone deficiency as a child, your growth hormone status should be retested after you have stopped growing. 
• If severe growth hormone deficiency is detected, the doctor may recommend that you continue treatment with Genotropin.

How To Use:

• Always use this medicine exactly as your doctor has told you.
• Contact the doctor, nurse or pharmacist if you are unsure.
• Genotropin is injected under the skin ( subcutaneous injection). 
• The usual dose is one injection per day. 
• The injection site must be varied to avoid skin irritation.

Instructions for use:

• Do not shake the solution.
• See separate instructions for use in the package for Genotropin MiniQuick, Genotropin pre-filled pen (GoQuick) or Genotropin Pen. If you do not remember what to do, do not attempt to give the injection. 
• Ask your doctor to see you again.
• When using an injection aid, the needle must be screwed on before mixing.
• Attach a new needle for each injection. Needles should never be reused.

If you take too much Genotropin:

• If you inject too much Genotropin, your blood sugar level may first become too low and then too high.

If you have forgotten to take Genotropin:

• If you have forgotten to take a dose one day, do not take a double dose the next day, but continue the treatment as usual.

Warnings and precautions:

Do not use Genotropin:

• If you are allergic to synthetic growth hormone (somatropin) or any of the other ingredients in this medicine.
• And tell your doctor if you have an active cancer . Cancer tumors must be inactive and you must have finished your cancer treatment before starting treatment with genotropin.
• If you become acutely ill with complications after major operations, injury or respiratory failure.
• As a growth stimulant for children who have finished growing.
• Talk to your doctor, pharmacist or nurse before using Genotropin.
• Genotropin can cause inflammation (inflammation) in the pancreas, which leads to severe pain in the stomach and back.
• Contact a doctor if you or your child gets stomach cramps after taking Genotropin.
• If you receive substitution treatment with glucocorticoids , you should consult your doctor regularly, as it may be necessary to adjust the dose of glucocorticoids .
• If you have a known risk of developing diabetes, your doctor will check your blood sugar level when you are treated with Genotropin.
• If you have diabetes, you should monitor your blood sugar levels carefully when you are treated with Genotropin. You should discuss the results with your doctor. It may be necessary to change the dose of the medicines you take to treat diabetes.
• Thyroid function should be checked regularly during treatment.
• Some patients may need to start treatment with thyroid hormone (thyroid hormone) after starting Genotropin treatment.
• If you are already receiving treatment with thyroid hormone, it may be necessary to adjust the dose of thyroid hormone.
• If you receive Genotropin treatment after you have been treated for cancer , you should be examined regularly for recurrence of the type of cancer you had, as well as for other types of cancer .
• If you take growth hormone to stimulate growth and you limp, or if you start limping during growth hormone treatment because of pain in your hip, you should tell your doctor.
• If you develop symptoms of increased pressure in the head (symptoms include severe and recurring headaches, visual disturbances, and nausea or vomiting), you must tell your doctor.
• In case of severe pain at the injection site, a doctor should be contacted.
• In patients with Prader-Willi syndrome : In the case of severe obesity, severely impaired breathing or sleep apnea, snoring, respiratory tract infection or blockage of the respiratory tract, a doctor should be contacted. If there are signs of a respiratory infection, a doctor must be contacted immediately. Control of weight must be followed up carefully before and during growth hormone treatment. The treatment should always be combined with a low-calorie diet.
• Renal function must be checked in patients with renal failure. The treatment must be discontinued in case of kidney transplantation.
• Experience with treating patients over 80 years of age is limited. Elderly people may be more sensitive to the effects of Genotropin.
• Talk to your doctor in particular if you are using or have recently used any of the following medicines.

 The doctor may need to adjust the dose of Genotropin or of the other medicines:

• Estrogens taken by mouth or other sex hormones.
• Medicines to treat diabetes.
• Thyroid hormones (thyroid hormones).
• Corticosteroids (such as cortisone or prednisolone).
• Cyclosporine (a drug that suppresses the immune system after a transplant).
• Medicines for the treatment of epilepsy (medicines against seizures).

Intake of Genotropin together with food and drink:

• Children with Prader-Willi syndrome will be given a diet by the doctor which they must follow along with the medication.

Pregnancy, breastfeeding and fertility:

• Talk to your doctor or pharmacist before taking this medicine if you are pregnant or breast-feeding, think you may be pregnant or plan to become pregnant.
• You should not use Genotropin if you are pregnant or trying to become pregnant. 
• There is little experience with the use of Genotropin during pregnancy.
  It is unknown whether Genotropin passes into breast milk.

Driving and using machines:

• Genotropin is not expected to affect the ability to drive or use machines.

Ingredients:

• Active Ingredient is somatropin.

What Genotropin looks like and the contents of the packGenotropin pre-filled syringe for single use (MiniQuick):

Available in the following strengths:

• 2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 1.0 mg, 1.2 mg, 1.4 mg, 1.6 mg, 1.8 mg and 2.0 mg without preservative. 
• Two-chamber ampoule in a pre-filled syringe for single use containing the prescribed dose. 
• When the plunger is turned, the contents of the two-chamber ampoule are mixed.